BSL-2 Macromolecular Crystallography Beamline (BL10U2) is one of the 16 beam lines constructed in the SSRF Phase-II project. This beamline is designed as a crystal diffraction data collection laboratory with a biosafety level-2 protection, in which virus structure and function research by crystal diffraction method is conducted. This beamline will support researchers to study the structure and function of the overall particles of pathogenic microorganisms (such as viruses, etc.) and transcriptional replication complexes, as well as clarify the molecular mechanism of pathogenic microorganisms infecting host cells and transcriptional replication. This beamline will strongly push the development of new, efficient and specific detection techniques, vaccines and therapeutic drugs.