The 20T ultra-highly uniform superconducting magnet (54 mm standard-bore) is coupled with a Bruker 850 MHz NMR spectrometer, featuring 5mm QCI H-P/C/N-D-5-Z and CP2.1 TCI 850 S6 (1H-13C/15N-2D) CryoProbes. The probes are equipped with automatic tuning and matching capabilities for optimal performance. The system is operated via a workstation running TopSpin 3.6 software, enabling a wide range of NMR experiments. These include 1D experiments for 1H, 13C, and 31P, as well as advanced 2D experiments (1H-1H, 1H-13C, 1H-15N and 1H-31P) and triple resonance techniques, which are responsible for structural study of biological macromolecular.
System Information
Operating field: 20 Tesla
NMR-frequency (1H): 850 MHz
Temperature: 277 K – 333 K
Room Temperature Bore Diameter：54 mm
Console：Bruker AVANCE III
Probe：CP2.1 TCI 850 S6 (1H-13C/15N-2D)/CP QCI 850 S6 (1H-31P/13C/15N-2D)
Sample Tube Diameter : 3 mm & 5 mm
Probe Sensitivity： 1H -9600，13C -1950/1H -6400，13C -1500
Application
Macromolecular structure determination, dynamics, interaction analysis and small molecular drug screening.
